| Etiology of embolism |
| | Arterial vascular disease |
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| Leading Causes of Mortality and Burden of Disease Worldwide |
| | Global projections for selected causes, 2004 to 2030 |
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| Red alert for women’s heart |
| | Arterial and Venous Thrombosis |
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| Atherosclerotic Plaque Progression |
| | Coagulation and the arterial vessel wall |
|
| Thrombus age after thrombosuction |
| | Histological spectrum of thrombus and atherosclerotic plaque tissue |
|
| IF STAININGS – CO-LOCALIZATION OF TF, FVII & FX |
| | EARLY ATHEROSCLEROSIS EXHIBITS AN ENHANCED PRO-COAGULANT STATE |
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| SIGNIFICANTLY HIGHER ETP & TAT IN EARLY ATHEROSCLEROTIC LESIONS |
| | Is the level of thrombin generated in blood clinically relevant? |
|
| Thrombin being proatherogenic? |
| | PHENOTYPIC MODULATION OF THE ARTERIAL VESSEL WALL |
|
| Thrombin and atherosclerosis: causality? |
| | EXTENSIVE ATHEROSCLEROSIS IN TM Pro/Pro / ApoE-/- CAROTID ARTERIES |
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| INCREASED ACCUMULATION OF MФ AND LESS α-ACTIN AND COLLAGEN I/III IN TM Pro/Pro / ApoE-/- |
| | INTRAPLAQUE HEMORRHAGE & PLAQUE RUPTURE IN TM Pro/Pro / ApoE-/- MICE |
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| INTRAPLAQUE HEMORRHAGE & PLAQUE RUPTURE IN MICE |
| | ENHANCED NEOANGIOGENESIS IN TM Pro/Pro / ApoE-/- MICE |
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| Clinical manifestations of atheroembolism |
|
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| Treatment? |
| | In the coagulation arena: new avenues? |
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| Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization |
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| Secondary prevention |
| | DABIGATRAN/APC PROTECTS AGAINST SEVERE ATHEROSCLEROSIS PROGRESSION IN TM Pro/Pro / ApoE-/- |
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| ResultsI/R injury : Evans Blue/TTC staining |
| | Antithrombotic therapy |
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